BDBM103905 JNK3 inhibitor 2::US8563583, C-1

SMILES COc1cc(ccc1OCCO)-n1ccc(cc1=O)-c1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=JCLKKRZMUZBICB-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 103905   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM103905(JNK3 inhibitor 2 | US8563583, C-1)
Affinity DataKi:  3nMpH: 7.4Assay Description:Compounds were characterized in an in vitro binding assay to determine their Ki or ability to antagonized binding of a peptide agonist to the human m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM103905(JNK3 inhibitor 2 | US8563583, C-1)
Affinity DataIC50:  136nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed