BDBM103911 JNK3 inhibitor 8::US8562945, 246

SMILES NOOSc1ccc(NC(=S)NCCCCCCCC[N]23CC4=CC=CC=[N]4[Re+]2[N]2=C(C3)C=CC=C2)cc1

InChI Key InChIKey=RWVAZDWYGSNEJK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 103911   

TargetCarbonic anhydrase 9(Homo sapiens (Human))
Molecular Insight Pharmaceuticals

US Patent
LigandPNGBDBM103911(JNK3 inhibitor 8 | US8562945, 246)
Affinity DataIC50:  42nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit carbonic anhydrase isozymes II and IX in vito.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM103911(JNK3 inhibitor 8 | US8562945, 246)
Affinity DataIC50:  3.15E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals

US Patent
LigandPNGBDBM103911(JNK3 inhibitor 8 | US8562945, 246)
Affinity DataIC50:  140nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit carbonic anhydrase isozymes II and IX in vito.More data for this Ligand-Target Pair
In DepthDetails US Patent