BDBM104127 US8575145, 4

SMILES C1C[C@@H](CN1)Nc1cccc2ccc(nc12)-c1nnc2ccccn12

InChI Key InChIKey=BNRNYCUKAUITIW-AWEZNQCLSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 104127   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM104127(US8575145, 4)
Affinity DataIC50:  22nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Rattus norvegicus (Rat))
Array Biopharma

US Patent
LigandPNGBDBM104127(US8575145, 4)
Affinity DataIC50:  105nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM104127(US8575145, 4)
Affinity DataIC50:  6.03E+3nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In DepthDetails US Patent