BDBM105135 US10047086, 66::US10640503, Example 66::US9695168, 66

SMILES CCN1CCC[C@@H](COc2cc(-c3ccc(cc3)C#N)c(-c3cnc4n(C)cnc4c3)n3cncc23)C1

InChI Key InChIKey=FAYOJFRUWROHOB-OAQYLSRUSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 105135   

TargetLysine-specific histone demethylase 1A [151-852](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM105135(US10047086, 66 | US10640503, Example 66 | US969516...)
Affinity DataIC50:  75nMpH: 7.5 T: 2°CAssay Description:LANCE LSD1/KDM1A demethylase assay¿10 uL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 mM Na...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM105135(US10047086, 66 | US10640503, Example 66 | US969516...)
Affinity DataIC50:  75nMAssay Description:LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM105135(US10047086, 66 | US10640503, Example 66 | US969516...)
Affinity DataIC50:  75nMpH: 7.5Assay Description:LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In DepthDetails US Patent