BDBM105193 4‐(1H‐imidazol‐1‐yl)phenol (Compound 1)::4-(1H-imidazol-1-yl)phenol

SMILES Oc1ccc(cc1)-n1ccnc1

InChI Key InChIKey=CYKCUAPYWQDIKR-UHFFFAOYSA-N

Data  5 IC50

PDB links: 4 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 105193   

TargetPolymerase acidic protein [1-204,T86I,G186S](2009 H1N1 Influenza)
Rutgers University

LigandPNGBDBM105193(4‐(1H‐imidazol‐1‐yl)phenol...)
Affinity DataIC50:  1.00E+6nMAssay Description:Cocktails of 4-8 compounds were used for the initial screening with single compound soaks to verify the bound fragment identity and to rule out coope...More data for this Ligand-Target Pair
TargetPolymerase acidic protein [1-204,T86I,G186S](2009 H1N1 Influenza)
Rutgers University

LigandPNGBDBM105193(4‐(1H‐imidazol‐1‐yl)phenol...)
Affinity DataIC50:  1.00E+6nMAssay Description:Cocktails of 4-8 compounds were used for the initial screening with single compound soaks to verify the bound fragment identity and to rule out coope...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
A*Star

Curated by ChEMBL
LigandPNGBDBM105193(4‐(1H‐imidazol‐1‐yl)phenol...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 (unknown origin) (72 to 385 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
A*Star

Curated by ChEMBL
LigandPNGBDBM105193(4‐(1H‐imidazol‐1‐yl)phenol...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of N-terminal GST-tagged MNK1 (unknown origin) (37 to 341 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM105193(4‐(1H‐imidazol‐1‐yl)phenol...)
Affinity DataIC50:  5.01E+5nMAssay Description:Inhibition of full length human C-terminal 6-His-tagged ATXbeta using FS-3 as substrate preincubated for 20 mins followed by substrate addition by fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed