BDBM106944 US8592468, EbSe2
SMILES O=c1[nH][se]c2ccccc12
InChI Key InChIKey=UELHWVKBVJWUPY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 106944
Affinity DataKi: 1.00E+3nM IC50: 1.50E+4nMAssay Description:All the benzisoselenazol-3(2H)-one and bisbenzisoselenazol-3(2H)-one
derivatives were tested as potential E. coli TrxR inhibitors by standard
DTNB ...More data for this Ligand-Target Pair
TargetUrease subunit beta(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Wroc?Aw University Of Technology
Curated by ChEMBL
Wroc?Aw University Of Technology
Curated by ChEMBL
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 using urea as substrate assessed as transformed cell u...More data for this Ligand-Target Pair
TargetUrease subunit beta(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Wroc?Aw University Of Technology
Curated by ChEMBL
Wroc?Aw University Of Technology
Curated by ChEMBL
Affinity DataIC50: 6.92E+3nMAssay Description:Inhibition of urease in Helicobacter pylori J99 in Brucella broth using urea as substrate preincubated for 2 hrs followed by substrate addition measu...More data for this Ligand-Target Pair
TargetMicrotubule-associated protein 2(Homo sapiens (Human))
Wroclaw University Of Technology
Curated by ChEMBL
Wroclaw University Of Technology
Curated by ChEMBL
Affinity DataIC50: 4.97E+3nMAssay Description:Non-covalent/mixed type inhibition of recombinant human MetAP2 using Met-AMC as substrate preincubated for 30 mins followed by substrate addition by ...More data for this Ligand-Target Pair
TargetUrease subunit beta(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Wroc?Aw University Of Technology
Curated by ChEMBL
Wroc?Aw University Of Technology
Curated by ChEMBL
Affinity DataIC50: 4.86E+4nMAssay Description:Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 using urea as substrate assessed as transformed cell u...More data for this Ligand-Target Pair