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BDBM107168 US8592426, 17

InChI string: InChI=1S/C25H21ClF4N4O3/c1-12-31-20(34-37-12)19-16(10-15(26)11-18(19)27)13-3-4-17-14(9-13)5-6-23(17,2)32-21(35)24(7-8-24)33-22(36)25(28,29)30/h3-4,9-11H,5-8H2,1-2H3,(H,32,35)(H,33,36)

SMILES: Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1ccc2c(CCC2(C)NC(=O)C2(CC2)NC(=O)C(F)(F)F)c1

InChI Key: InChIKey=HJCJUXBDBHUVCI-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 107168   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107168
PNG
(US8592426, 17)
Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1ccc2c(CCC2(C)NC(=O)C2(CC2)NC(=O)C(F)(F)F)c1
Show InChI InChI=1S/C25H21ClF4N4O3/c1-12-31-20(34-37-12)19-16(10-15(26)11-18(19)27)13-3-4-17-14(9-13)5-6-23(17,2)32-21(35)24(7-8-24)33-22(36)25(28,29)30/h3-4,9-11H,5-8H2,1-2H3,(H,32,35)(H,33,36)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
5.90n/an/an/an/an/an/an/an/a



Hoffmann—La Roche Inc.

US Patent


Assay Description
Binding assay using Bradykinin-1 receptor.


US Patent US8592426 (2013)

More data for this
Ligand-Target Pair
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107168
PNG
(US8592426, 17)
Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1ccc2c(CCC2(C)NC(=O)C2(CC2)NC(=O)C(F)(F)F)c1
Show InChI InChI=1S/C25H21ClF4N4O3/c1-12-31-20(34-37-12)19-16(10-15(26)11-18(19)27)13-3-4-17-14(9-13)5-6-23(17,2)32-21(35)24(7-8-24)33-22(36)25(28,29)30/h3-4,9-11H,5-8H2,1-2H3,(H,32,35)(H,33,36)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/a 0.600n/an/an/an/an/an/a



Hoffmann—La Roche Inc.

US Patent


Assay Description
Calcium mobilization assay using Bradykinin-1 receptor.


US Patent US8592426 (2013)

More data for this
Ligand-Target Pair