BDBM107478 US8592410, 18

SMILES C[C@H](N1CC[C@@](CC(C)(C)O)(OC1=O)c1ccccc1)c1ccc(cc1)-c1nn(C)c(=O)cc1C

InChI Key InChIKey=CEYMUNJCMDJNBN-MMTVBGGISA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 107478   

TargetCytochrome P450 3A4(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM107478(US8592410, 18)
Affinity DataIC50: >5.00E+4nMT: 2°CAssay Description:The assay was based on a method published by Moody et al. (Xenobiotica 1999). The inhibition of cytochrome P450 3A4-isoenzyme catalysed N-demethylati...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2C19(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM107478(US8592410, 18)
Affinity DataIC50: >5.00E+4nMAssay Description:Using a procedure similar to that described in Biological Test Example 6, the inhibition of cytochrome P450 2C19-isoenzyme catalysed N-demethylation ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2C9(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM107478(US8592410, 18)
Affinity DataIC50: >5.00E+4nMT: 2°CAssay Description:Using a procedure similar to that described in Biological Test Example 6, the inhibition of cytochrome P450 2C9-isoenzyme catalysed O-demethylation o...More data for this Ligand-Target Pair
In DepthDetails US Patent