BDBM108056 4-((4-((2,3-dimethyl-2H-indazole-6-yl)amino) pyrimidin-2-yl)amino)-N-(5-methylisoxazol-3-yl) benzenesulfonamide (P1f)

SMILES Cc1cc(NS(=O)(=O)c2ccc(Nc3nccc(Nc4ccc5c(C)n(C)nc5c4)n3)cc2)no1

InChI Key InChIKey=OLOGECLSWUOJTL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 108056   

TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Shandong Institute Of Pharmaceutical Industry

LigandPNGBDBM108056(4-((4-((2,3-dimethyl-2H-indazole-6-yl)amino) pyrim...)
Affinity DataIC50:  2.18E+3nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Shandong Institute Of Pharmaceutical Industry

LigandPNGBDBM108056(4-((4-((2,3-dimethyl-2H-indazole-6-yl)amino) pyrim...)
Affinity DataIC50:  1.63E+3nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed