BDBM10818 3-[2-(prop-2-yn-1-ylamino)propyl]phenyl N,N-dimethylcarbamate::Phenethylamine deriv. 52a

SMILES CC(Cc1cccc(OC(=O)N(C)C)c1)NCC#C

InChI Key InChIKey=JVHQRHHNABNBOK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 10818   

TargetAcetylcholinesterase(Homo sapiens (Human))
Teva Pharmaceutical Industries

LigandPNGBDBM10818(3-[2-(prop-2-yn-1-ylamino)propyl]phenyl N,N-dimeth...)
Affinity DataIC50:  540nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Teva Pharmaceutical Industries

LigandPNGBDBM10818(3-[2-(prop-2-yn-1-ylamino)propyl]phenyl N,N-dimeth...)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Teva Pharmaceutical Industries

LigandPNGBDBM10818(3-[2-(prop-2-yn-1-ylamino)propyl]phenyl N,N-dimeth...)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Teva Pharmaceutical Industries

LigandPNGBDBM10818(3-[2-(prop-2-yn-1-ylamino)propyl]phenyl N,N-dimeth...)
Affinity DataIC50:  1.09E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed