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BDBM108281 US8604046, 61

SMILES: CC(C)(C)OC(=O)N1CCC2(CCCN(C2=O)c2ccc(cc2F)N2CC[C@@H](C2)N2CCCC2)CC1

InChI Key: InChIKey=UADXMEPSNMRPAA-QFIPXVFZSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 108281   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108281
PNG
(US8604046, 61)
Show SMILES CC(C)(C)OC(=O)N1CCC2(CCCN(C2=O)c2ccc(cc2F)N2CC[C@@H](C2)N2CCCC2)CC1
Show InChI InChI=1S/C28H41FN4O3/c1-27(2,3)36-26(35)31-17-11-28(12-18-31)10-6-15-33(25(28)34)24-8-7-21(19-23(24)29)32-16-9-22(20-32)30-13-4-5-14-30/h7-8,19,22H,4-6,9-18,20H2,1-3H3/t22-/m0/s1
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
0.0300n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair