BindingDB logo
myBDB logout

BDBM108308 US8604046, 88

SMILES: C[C@H]1CCCCN1[C@H]1CCN(C1)c1ccc(N2CCC3(CCNCC3)C2=O)c(F)c1

InChI Key: InChIKey=RPKFQOHFLHMANE-ICSRJNTNSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 108308   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))
BDBM108308
PNG
(US8604046, 88)
Show SMILES C[C@H]1CCCCN1[C@H]1CCN(C1)c1ccc(N2CCC3(CCNCC3)C2=O)c(F)c1
Show InChI InChI=1S/C24H35FN4O/c1-18-4-2-3-13-28(18)20-7-14-27(17-20)19-5-6-22(21(25)16-19)29-15-10-24(23(29)30)8-11-26-12-9-24/h5-6,16,18,20,26H,2-4,7-15,17H2,1H3/t18-,20-/m0/s1
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
0.5n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...


US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair