BDBM10894 4-(4-tert-Butylphenylcarboxamidomethyl)benzenesulfonamide::4-tert-butyl-N-[(4-sulfamoylphenyl)methyl]benzamide::aromatic/heteroaromatic sulfonamide 28

SMILES CC(C)(C)c1ccc(cc1)C(=O)NCc1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=MLMBOLOCASDIAK-UHFFFAOYSA-N

Data  3 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 10894   

TargetCARBONIC ANHYDRASE(Helicobacter pylori J99)
Kochi Medical School

LigandPNGBDBM10894(4-(4-tert-Butylphenylcarboxamidomethyl)benzenesulf...)
Affinity DataKi:  62nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10894(4-(4-tert-Butylphenylcarboxamidomethyl)benzenesulf...)
Affinity DataKi:  127nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10894(4-(4-tert-Butylphenylcarboxamidomethyl)benzenesulf...)
Affinity DataKi:  1.33E+4nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM10894(4-(4-tert-Butylphenylcarboxamidomethyl)benzenesulf...)
Affinity DataEC50:  1.40E+3nMAssay Description:Inhibition of recombinant v-Abl tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM10894(4-(4-tert-Butylphenylcarboxamidomethyl)benzenesulf...)
Affinity DataIC50:  280nMAssay Description:Inhibition of recombinant human sEH using PHOME as substrate preincubated for 30 mins followed by substrate addition measured for 30 mins by fluoresc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed