BDBM109082 US10793535, Cmpd ID 666::US8604016, 666::US9938267, Cmpd ID 666

SMILES FC(F)Oc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1

InChI Key InChIKey=KRTRGYMEOYWRKI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 109082   

TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Calithera Biosciences

US Patent
LigandPNGBDBM109082(US10793535, Cmpd ID 666 | US8604016, 666 | US99382...)
Affinity DataIC50:  4nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences

US Patent
LigandPNGBDBM109082(US10793535, Cmpd ID 666 | US8604016, 666 | US99382...)
Affinity DataIC50:  4nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Calithera Biosciences

US Patent
LigandPNGBDBM109082(US10793535, Cmpd ID 666 | US8604016, 666 | US99382...)
Affinity DataIC50:  4nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent