BDBM109873 US8609647, 16

SMILES CC1CN(CC2(CCN2C(=O)CC#N)C1)c1ncnc2[nH]ccc12

InChI Key InChIKey=MZMDRPCGALXDIS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 109873   

TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Japan Tobacco

US Patent
LigandPNGBDBM109873(US8609647, 16)
Affinity DataIC50:  58nMAssay Description:In the kinase reactions, fused proteins (6His tag-fused hJAK3 kinase domain (aa781-end)) which were coexpressed in Sf21 cells and purified by Ni2+/NT...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM109873(US8609647, 16)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full-length human Lck using TK-substrate-biotin as substrate incubated for 60 mins in presence of AT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Japan Tobacco

US Patent
LigandPNGBDBM109873(US8609647, 16)
Affinity DataIC50:  58nMAssay Description:Inhibition of human JAK3 (780 to end residues) expressed in baculovirus infected Sf9 cells using TK-substrate-biotin as substrate incubated for 60 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed