BDBM110645 US8614234, 113::US9725433, 113

SMILES COCCOC(=O)c1c[nH]c(c1)-c1cc(Oc2ccc(NC(=O)Nc3cc(C)ccc3F)cc2)ccn1

InChI Key InChIKey=LDZCJDGPCDLDBR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 110645   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM110645(US8614234, 113 | US9725433, 113)
Affinity DataIC50:  25nMAssay Description:Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of VEGF induced increases in intracellular calcium l...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM110645(US8614234, 113 | US9725433, 113)
Affinity DataIC50:  25nMpH: 7.2 T: 2°CAssay Description:Kinase assays were performed in 96 well microtiter plates that were coated overnight with 30.mu.g of poly-Glu-Tyr (4:1) in 10 mM Phosphate Buffered S...More data for this Ligand-Target Pair
In DepthDetails US Patent