BDBM111628 US8618111, B-15

SMILES [#6]-[#6]-c1ncnc(-[#7]-2-[#6]-[#6]-[#6](-[#6]-[#6]-2)\[#6]=[#6](\[#6])-[#6])c1C#Cc1ccc(-[#7])nc1

InChI Key InChIKey=WPKCXIBHOZSFMI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 111628   

TargetSerine/threonine-protein kinase mTOR(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111628(US8618111, B-15)
Affinity DataIC50:  64nMpH: 7.5 T: 25°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM111628(US8618111, B-15)
Affinity DataIC50:  622nMpH: 7.5 T: 0°CAssay Description:PI3Kalpha assay described herein provides IC50 values indicating the activity of the compounds inhibiting PI3 kinase alpha activity Inhibition of PI3...More data for this Ligand-Target Pair
In DepthDetails US Patent