BDBM112483 US8623885, 24

SMILES C[C@H]1CC[C@@H](CC1)n1c2cnccc2c2cnc(Nc3cc4CCNCc4cn3)nc12

InChI Key InChIKey=QCXIUEONPAEKGB-RZDIXWSQSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 112483   

TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM112483(US8623885, 24)
Affinity DataIC50:  4.70nMpH: 7.4Assay Description:The CDK4 and CDK1 inhibitory activity of the CDK4/6-FLT3 inhibitors was determined with a filtration kinase assay. The compounds, kinase and substrat...More data for this Ligand-Target Pair
In DepthDetails US Patent