BDBM11263 dipeptidomimetic unsaturated ester 18e::ethyl (2E,4S)-4-({N-[(2E)-3-(1,3-benzodioxol-5-yl)prop-2-enoyl]-L-phenylalanyl}amino)-5-phenylpent-2-enoate::ethyl (2E,4S)-4-[(2S)-2-[(2E)-3-(2H-1,3-benzodioxol-5-yl)prop-2-enamido]-3-phenylpropanamido]-5-phenylpent-2-enoate

SMILES CCOC(=O)\C=C\[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)\C=C\c1ccc2OCOc2c1

InChI Key InChIKey=PQLARAJPSQMPIR-PKDKPTJCSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11263   

TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Taiwan University

LigandPNGBDBM11263(dipeptidomimetic unsaturated ester 18e | ethyl (2E...)
Affinity DataKi:  3.05E+3nM ΔG°:  -7.52kcal/mole IC50:  7.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed