BDBM112647 US10112950, Example 116::US10556908, Example 116::US9695180, 116
SMILES COc1cc(cnc1C)-c1c(nc(N2CCC(CC2)N(C)C)c2nccn12)-c1ccc(cc1)C#N
InChI Key InChIKey=SIXXHQQUKXKBLD-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 112647
Affinity DataIC50: 275nMpH: 7.5 T: 2°CAssay Description:10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 mM NaCl, 5 mM DTT) were preincubated ...More data for this Ligand-Target Pair
Affinity DataIC50: 275nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
Affinity DataIC50: 275nMpH: 7.5Assay Description:LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair