BDBM112740 US8629141, 7

SMILES Fc1c(Cl)cccc1[C@H]1[C@@H](NC2(CCC(F)(F)CC2)[C@@]11C(=O)Nc2cc(Cl)ccc12)C(=O)NCCN1CCOCC1

InChI Key InChIKey=DUUKXUBPZCGIEL-IQANXLHVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 112740   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112740(US8629141, 7)
Affinity DataIC50: <1.00E+3nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent