BDBM112751 US8629141, 18

SMILES CNC(=O)[C@@H]1NC2(CCN(CC2)C(C)=O)[C@@]2([C@H]1c1cccc(Cl)c1F)C(=O)Nc1cc(Cl)ccc21

InChI Key InChIKey=REHJJNQNQSNLAN-HWHXTQLESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 112751   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112751(US8629141, 18)
Affinity DataIC50: >5.00E+3nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent