BDBM113472 US8633204, 183
SMILES CO[C@H]1CC[C@@H](CC1)n1c2nc(N)nc(C)c2cc(-c2cn[nH]c2)c1=O
InChI Key InChIKey=MSWXKPHFXJRTLF-JOCQHMNTSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 113472
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 9nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair