BDBM11506 (2S,3S)-1-[(3S)-3-fluoropyrrolidin-1-yl]-1-oxo-3-{4-[4-(trifluoromethyl)phenyl]phenyl}butan-2-aminium; 2,2,2-trifluoroacetate::3-(S)-fluoropyrrolidide 26

SMILES C[C@H]([C@H]([NH3+])C(=O)N1CC[C@H](F)C1)c1ccc(cc1)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=GLXIREWNAUAUFX-AGRHKRQWSA-O

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 11506   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM11506((2S,3S)-1-[(3S)-3-fluoropyrrolidin-1-yl]-1-oxo-3-{...)
Affinity DataIC50:  510nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM11506((2S,3S)-1-[(3S)-3-fluoropyrrolidin-1-yl]-1-oxo-3-{...)
Affinity DataIC50: >1.00E+5nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM11506((2S,3S)-1-[(3S)-3-fluoropyrrolidin-1-yl]-1-oxo-3-{...)
Affinity DataIC50:  6.40E+4nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM11506((2S,3S)-1-[(3S)-3-fluoropyrrolidin-1-yl]-1-oxo-3-{...)
Affinity DataIC50:  670nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed