BDBM11592 5-(aminomethyl)-6-(2,4-dichlorophenyl)-2-(3,4-difluorophenyl)pyrimidin-4-amine::Aminomethylpyrimidine 1d

SMILES NCc1c(N)nc(nc1-c1ccc(Cl)cc1Cl)-c1ccc(F)c(F)c1

InChI Key InChIKey=RSTRFELFAGTRRB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11592   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Hoffmann-La Roche

LigandPNGBDBM11592(5-(aminomethyl)-6-(2,4-dichlorophenyl)-2-(3,4-difl...)
Affinity DataIC50:  3nMAssay Description:DPP-IV inhibitors were measured for their ability to inhibit DPP-IV mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed