BDBM116307 US8637504, 104::US9273053, 104::US9650371, 104

SMILES COc1cnc(cn1)C(=O)Nc1cncc(c1)[C@]1(C)CC(=C)SC(N)=N1

InChI Key InChIKey=FWRHQSSBQXQXID-KRWDZBQOSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 116307   

TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM116307(US8637504, 104 | US9273053, 104 | US9650371, 104)
Affinity DataIC50:  63nMpH: 5.0 T: 2°CAssay Description:48.5 μL of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=ε-amino-n-capronic acid, Eu=Europium cryptate) was added to each well ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM116307(US8637504, 104 | US9273053, 104 | US9650371, 104)
Affinity DataIC50:  63nMAssay Description:48.5 uL of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=ε-amino-n-capronic acid, Eu=Europium cryptate) was added to each well of...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM116307(US8637504, 104 | US9273053, 104 | US9650371, 104)
Affinity DataIC50:  63nMpH: 5.0Assay Description:48.5 μL of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=ε-amino-n-capronic acid, Eu=Europium cryptate) was added to each well ...More data for this Ligand-Target Pair
In DepthDetails US Patent