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BDBM116311 US8637528, OM955

SMILES: CCCOc1ccc(Cl)c2NC(=O)NC3(CCCCC3)c12

InChI Key: InChIKey=LMANVTDDCGUCNF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 116311   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 7B


(Homo sapiens (Human))
BDBM116311
PNG
(US8637528, OM955)
Show SMILES CCCOc1ccc(Cl)c2NC(=O)NC3(CCCCC3)c12
Show InChI InChI=1S/C16H21ClN2O2/c1-2-10-21-12-7-6-11(17)14-13(12)16(19-15(20)18-14)8-4-3-5-9-16/h6-7H,2-5,8-10H2,1H3,(H2,18,19,20)
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PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 106n/an/an/an/a8.0n/a



Omeros Corporation

US Patent


Assay Description
The assay method used was a scintillation proximity assay (SPA) (obtained from GE Healthcare, Product Code TRKQ7100), with [3H]-cGMP as the substrate...


US Patent US8637528 (2014)


BindingDB Entry DOI: 10.7270/Q29022FT
More data for this
Ligand-Target Pair
Phosphodiesterase 7


(Homo sapiens (Human))
BDBM116311
PNG
(US8637528, OM955)
Show SMILES CCCOc1ccc(Cl)c2NC(=O)NC3(CCCCC3)c12
Show InChI InChI=1S/C16H21ClN2O2/c1-2-10-21-12-7-6-11(17)14-13(12)16(19-15(20)18-14)8-4-3-5-9-16/h6-7H,2-5,8-10H2,1H3,(H2,18,19,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 51.8n/an/an/an/a8.0n/a



Omeros Corporation

US Patent


Assay Description
The assay method used was a scintillation proximity assay (SPA) (obtained from GE Healthcare, Product Code TRKQ7100), with [3H]-cGMP as the substrate...


US Patent US8637528 (2014)


BindingDB Entry DOI: 10.7270/Q29022FT
More data for this
Ligand-Target Pair