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BDBM116510 US8637532, 193

SMILES: Cc1ccc(CNc2ncnc3c(cccc23)C(N)=O)cc1C

InChI Key: InChIKey=CKSGWNWLYXUENQ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 116510   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase (P70S6K)


(Homo sapiens (Human))
BDBM116510
PNG
(US8637532, 193)
Show SMILES Cc1ccc(CNc2ncnc3c(cccc23)C(N)=O)cc1C
Show InChI InChI=1S/C18H18N4O/c1-11-6-7-13(8-12(11)2)9-20-18-15-5-3-4-14(17(19)23)16(15)21-10-22-18/h3-8,10H,9H2,1-2H3,(H2,19,23)(H,20,21,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 0.530n/an/an/an/a7.525



Merck Patent GmbH

US Patent


Assay Description
P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...


US Patent US8637532 (2014)


BindingDB Entry DOI: 10.7270/Q21G0JZX
More data for this
Ligand-Target Pair