BDBM11705 (2S)-Cyanopyrrolidine analogue 18i::CHEMBL382907::N-Benzyl-3-[2-(2-cyano-(S)-pyrrolidin-1-yl)-2-oxoethylamino]-propionamide::N-benzyl-3-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}amino)propanamide

SMILES O=C(CCNCC(=O)N1CCC[C@H]1C#N)NCc1ccccc1

InChI Key InChIKey=XGTIVPZSNDKUFO-HNNXBMFYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 11705   

TargetDipeptidyl peptidase 4(Human)
National Health Research Institutes

LigandPNGBDBM11705((2S)-Cyanopyrrolidine analogue 18i | CHEMBL382907 ...)
Affinity DataIC50:  452nMpH: 8.0 T: 37°CAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Human)
National Health Research Institutes

LigandPNGBDBM11705((2S)-Cyanopyrrolidine analogue 18i | CHEMBL382907 ...)
Affinity DataIC50:  1.07E+4nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Human)
National Health Research Institutes

LigandPNGBDBM11705((2S)-Cyanopyrrolidine analogue 18i | CHEMBL382907 ...)
Affinity DataIC50:  1.74E+4nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Human)
National Health Research Institutes

LigandPNGBDBM11705((2S)-Cyanopyrrolidine analogue 18i | CHEMBL382907 ...)
Affinity DataIC50:  452nMAssay Description:In vitro inhibition of DPP-4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Human)
National Health Research Institutes

LigandPNGBDBM11705((2S)-Cyanopyrrolidine analogue 18i | CHEMBL382907 ...)
Affinity DataIC50:  1.07E+4nMAssay Description:In vitro inhibition of DPP-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Human)
National Health Research Institutes

LigandPNGBDBM11705((2S)-Cyanopyrrolidine analogue 18i | CHEMBL382907 ...)
Affinity DataIC50:  1.74E+4nMAssay Description:In vitro inhibition of DPP-IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase FAP(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM11705((2S)-Cyanopyrrolidine analogue 18i | CHEMBL382907 ...)
Affinity DataIC50: >2.00E+4nMAssay Description:In vitro inhibition of FAP, sepraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed