BDBM11717 (2S)-1-(2-{[4-(6-fluoro-1,2,3,4-tetrahydroisoquinolin-2-yl)-2-methyl-4-oxobutan-2-yl]amino}acetyl)pyrrolidine-2-carbonitrile::(2S)-Cyanopyrrolidine analogue 21b::2-[3-[2-[2-Cyano-(S)-pyrrolidin-1-yl]-2-oxoethylamino]-3-methyl-1-oxobutyl]-6-fluoro-1,2,3,4-tetrahydroisoquinoline

SMILES CC(C)(CC(=O)N1CCc2cc(F)ccc2C1)NCC(=O)N1CCC[C@H]1C#N

InChI Key InChIKey=ZIIKZTJCIIXHID-SFHVURJKSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 11717   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
National Health Research Institutes

LigandPNGBDBM11717((2S)-1-(2-{[4-(6-fluoro-1,2,3,4-tetrahydroisoquino...)
Affinity DataIC50:  30nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
National Health Research Institutes

LigandPNGBDBM11717((2S)-1-(2-{[4-(6-fluoro-1,2,3,4-tetrahydroisoquino...)
Affinity DataIC50:  5.01E+4nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
National Health Research Institutes

LigandPNGBDBM11717((2S)-1-(2-{[4-(6-fluoro-1,2,3,4-tetrahydroisoquino...)
Affinity DataIC50: >1.00E+5nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed