BDBM11720 (2S)-Cyanopyrrolidine analogue 21e::3-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}amino)-3-methyl-N-(2-phenylpropan-2-yl)butanamide::3-[2-(2-Cyanopyrrolidin-1-yl)-2-oxo-ethylamino]-3-methyl-N-(1-methyl-1-phenylethyl)butyramide::CHEMBL202711

SMILES CC(C)(CC(=O)NC(C)(C)c1ccccc1)NCC(=O)N1CCC[C@H]1C#N

InChI Key InChIKey=GAALJUPHNLYJNQ-KRWDZBQOSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 11720   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
National Health Research Institutes

LigandPNGBDBM11720((2S)-Cyanopyrrolidine analogue 21e | 3-({2-[(2S)-2...)
Affinity DataIC50:  1.11E+3nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
National Health Research Institutes

LigandPNGBDBM11720((2S)-Cyanopyrrolidine analogue 21e | 3-({2-[(2S)-2...)
Affinity DataIC50: >1.00E+5nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
National Health Research Institutes

LigandPNGBDBM11720((2S)-Cyanopyrrolidine analogue 21e | 3-({2-[(2S)-2...)
Affinity DataIC50: >1.00E+5nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
National Health Research Institutes

LigandPNGBDBM11720((2S)-Cyanopyrrolidine analogue 21e | 3-({2-[(2S)-2...)
Affinity DataIC50: >2.00E+4nMAssay Description:In vitro inhibition of DPP-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
National Health Research Institutes

LigandPNGBDBM11720((2S)-Cyanopyrrolidine analogue 21e | 3-({2-[(2S)-2...)
Affinity DataIC50: >2.00E+4nMAssay Description:In vitro inhibition of DPP-IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
National Health Research Institutes

LigandPNGBDBM11720((2S)-Cyanopyrrolidine analogue 21e | 3-({2-[(2S)-2...)
Affinity DataIC50:  1.11E+3nMAssay Description:In vitro inhibition of DPP-4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM11720((2S)-Cyanopyrrolidine analogue 21e | 3-({2-[(2S)-2...)
Affinity DataIC50: >2.00E+4nMAssay Description:In vitro inhibition of FAP, sepraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed