BDBM11826 Azepane Derivative 7::N-((3R,4R)-4-{[4-(2-fluoro-6-hydroxy-3-methoxybenzoyl)benzyl]amino}azepan-3-yl)isonicotinamide trihydrochloride::N-[(3R,4R)-4-[({4-[(2-fluoro-6-hydroxy-3-methoxyphenyl)carbonyl]phenyl}methyl)amino]azepan-3-yl]pyridine-4-carboxamide trihydrochloride

SMILES COc1ccc(O)c(C(=O)c2ccc(CN[C@@H]3CCCNC[C@H]3NC(=O)c3ccncc3)cc2)c1F

InChI Key InChIKey=IJSCWNUPUAQTRD-NHCUHLMSSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 11826   

TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Roche Diagnostics

LigandPNGBDBM11826(Azepane Derivative 7 | N-((3R,4R)-4-{[4-(2-fluoro-...)
Affinity DataIC50:  800nMpH: 7.2 T: 2°CAssay Description:In this assay, a fluorescent phosphopeptide tracer and the nonfluorescent phosphopeptides generated during a PKA reaction compete for binding to an a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Roche Diagnostics

LigandPNGBDBM11826(Azepane Derivative 7 | N-((3R,4R)-4-{[4-(2-fluoro-...)
Affinity DataIC50:  3.00E+3nMpH: 7.5 T: 2°CAssay Description:An ELISA-based assay has been developed for the serine/threonine kinase, PKB-alpha. The assay utilizes an N-terminally biotinylated substrate peptide...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed