BDBM11894 (2S)-2-amino-N-(cyanomethyl)-3,3-dimethyl-N-(prop-2-en-1-yl)butanamide::seco-proline-based inhibitor 10
SMILES [H][C@@](N)(C(=O)N(CC=C)CC#N)C(C)(C)C
InChI Key InChIKey=HMECNQNCYAFYFS-SECBINFHSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 11894
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Bristol-Myers Squibb Pharmaceutical Research Institute
Affinity DataKi: 212nM ΔG°: -9.01kcal/molepH: 7.4 T: 2°CAssay Description:Inhibition of human DPP-IV activity was measured under steady-state conditions by following the absorbance increase at 405 nm upon the substrate clea...More data for this Ligand-Target Pair