BDBM11895 (2S)-2-amino-N-(cyanomethyl)-N-cyclopropyl-3,3-dimethylbutanamide::seco-proline-based inhibitor 11

SMILES [H][C@@](N)(C(=O)N(CC#N)C1CC1)C(C)(C)C

InChI Key InChIKey=WTNOSBRNUHGJFQ-SECBINFHSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11895   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM11895((2S)-2-amino-N-(cyanomethyl)-N-cyclopropyl-3,3-dim...)
Affinity DataKi:  1.31E+3nM ΔG°:  -7.94kcal/molepH: 7.4 T: 2°CAssay Description:Inhibition of human DPP-IV activity was measured under steady-state conditions by following the absorbance increase at 405 nm upon the substrate clea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed