BDBM11895 (2S)-2-amino-N-(cyanomethyl)-N-cyclopropyl-3,3-dimethylbutanamide::seco-proline-based inhibitor 11
SMILES [H][C@@](N)(C(=O)N(CC#N)C1CC1)C(C)(C)C
InChI Key InChIKey=WTNOSBRNUHGJFQ-SECBINFHSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 11895
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Bristol-Myers Squibb Pharmaceutical Research Institute
Affinity DataKi: 1.31E+3nM ΔG°: -7.94kcal/molepH: 7.4 T: 2°CAssay Description:Inhibition of human DPP-IV activity was measured under steady-state conditions by following the absorbance increase at 405 nm upon the substrate clea...More data for this Ligand-Target Pair