BDBM119406 US8669361, 353::US9573943, Example 353
SMILES Nc1sc(nc1C(=O)Nc1cnn(CCF)c1)-c1c(F)cccc1F
InChI Key InChIKey=XCFKWUCNYGYTAY-UHFFFAOYSA-N
Data 6 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 119406
Affinity DataKi: 11.9nMpH: 7.2Assay Description:PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...More data for this Ligand-Target Pair
Affinity DataKi: 11.9nM ΔG°: -10.8kcal/molepH: 7.2 T: 2°CAssay Description:PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...More data for this Ligand-Target Pair
Affinity DataKi: 19nM ΔG°: -10.5kcal/molepH: 7.2 T: 2°CAssay Description:PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...More data for this Ligand-Target Pair
Affinity DataKi: 19nMpH: 7.2Assay Description:PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...More data for this Ligand-Target Pair
Affinity DataKi: 38nM ΔG°: -10.1kcal/molepH: 7.2 T: 2°CAssay Description:PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...More data for this Ligand-Target Pair
Affinity DataKi: 38nMpH: 7.2Assay Description:PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...More data for this Ligand-Target Pair