BDBM119438 BDBM119693::US8685986, 12

SMILES ONC(=O)c1ccc(CNC(=O)c2[nH]c(cc2-c2ccc(F)cc2)-c2ccoc2)cc1

InChI Key InChIKey=CNOWOXXSYNLOJR-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 119438   

TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ube Industries

US Patent
LigandPNGBDBM119438(BDBM119693 | US8685986, 12)
Affinity DataKi:  1.10nM ΔG°:  -12.4kcal/molepH: 6.0 T: 2°CAssay Description:Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Universidad Del PaíS Vasco

US Patent
LigandPNGBDBM119438(BDBM119693 | US8685986, 12)
Affinity DataIC50:  124nMT: 2°CAssay Description:The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
Universidad Del PaíS Vasco

US Patent
LigandPNGBDBM119438(BDBM119693 | US8685986, 12)
Affinity DataIC50:  451nMT: 2°CAssay Description:The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Universidad Del PaíS Vasco

US Patent
LigandPNGBDBM119438(BDBM119693 | US8685986, 12)
Affinity DataIC50:  42.8nMT: 2°CAssay Description:The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Universidad Del PaíS Vasco

US Patent
LigandPNGBDBM119438(BDBM119693 | US8685986, 12)
Affinity DataIC50:  384nMT: 2°CAssay Description:The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
Universidad Del PaíS Vasco

US Patent
LigandPNGBDBM119438(BDBM119693 | US8685986, 12)
Affinity DataIC50:  1.15E+3nMT: 2°CAssay Description:The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly...More data for this Ligand-Target Pair
In DepthDetails US Patent