BDBM119844 US8691986, 10

SMILES CNC(=O)c1ccc(cc1F)-c1nccnc1C1CN(C1)c1ncc2ccc(Cl)cc2n1

InChI Key InChIKey=MLXZHNCPMBZZCF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 119844   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM119844(US8691986, 10)
Affinity DataIC50:  7.38E+3nMpH: 7.2 T: 2°CAssay Description:IMAP TR-FRET progressive binding system, FAM-cAMP substrate were from Molecular Devices (Sunnyvale, Calif.). The PDE IMAP assay was conducted in a 3...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM119844(US8691986, 10)
Affinity DataIC50:  5.90nMpH: 7.2 T: 2°CAssay Description:IMAP TR-FRET progressive binding system, FAM-cAMP substrate were from Molecular Devices (Sunnyvale, Calif.). The PDE IMAP assay was conducted in a 3...More data for this Ligand-Target Pair
In DepthDetails US Patent