BDBM120002 US8697911, 201

SMILES CN1CCc2ccc(NC(=O)c3cccc(CNC(=O)N4CCc5c4cccc5C#N)c3)cc2C1

InChI Key InChIKey=DPYQBASTYQLBBZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 120002   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM120002(US8697911, 201)
Affinity DataIC50:  34nMpH: 7.2Assay Description:This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM120002(US8697911, 201)
Affinity DataIC50:  6.90nMpH: 7.5 T: 2°CAssay Description:The activity of ROCKII (1-543) kinase is measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent