BDBM120108 US8697715, 134::US9259470, 134

SMILES CC[C@@H](CO)Nc1nccc(n1)-c1ccn(C(C)c2ccc(Cl)c(F)c2)c(=O)c1

InChI Key InChIKey=VRSWMZNGLRKWNW-VYIIXAMBSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 120108   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM120108(US8697715, 134 | US9259470, 134)
Affinity DataIC50:  5.5nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM120108(US8697715, 134 | US9259470, 134)
Affinity DataIC50:  5.5nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In DepthDetails US Patent