BDBM120129 US8697708, 9

SMILES COC(=O)Nc1nccc2nc(sc12)-c1c(Cl)cccc1Cl

InChI Key InChIKey=DFJZFXVVYQXPRA-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 120129   

TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM120129(US8697708, 9)
Affinity DataKi:  1.40nM ΔG°:  -11.9kcal/molepH: 7.2 T: 2°CAssay Description:To determine the inhibition constants (Ki) of Examples 1-240, compounds were diluted serially in DMSO and added to 50 μL kinase reactions contai...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent