BDBM12013 4-(AMINOSULFONYL)-N-PHENYLMETHYLBENZAMIDE::CHEMBL302715::N-benzyl-4-sulfamoylbenzamide::SBB

SMILES: NS(=O)(=O)c1ccc(cc1)C(=O)NCc1ccccc1

InChI Key: InChIKey=CZKNSZUJCJHTTM-UHFFFAOYSA-N

Data: 2 Kd

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12013   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM12013 (4-(AMINOSULFONYL)-N-PHENYLMETHYLBENZAMIDE | CHEMBL...) Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C14H14N2O3S/c15-20(18,19)13-8-6-12(7-9-13)14(17)16-10-11-4-2-1-3-5-11/h1-9H,10H2,(H,16,17)(H2,15,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a
Harvard University Curated by ChEMBL					Assay Description Dissociation constant against human Carbonic anhydrase II (HCA II)				J Med Chem 37: 2100-5 (1994) Article DOI: 10.1021/jm00039a023 BindingDB Entry DOI: 10.7270/Q2TX3DDV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic Anhydrase II Mutant (F131V) (Homo sapiens (Human))	BDBM12013 (4-(AMINOSULFONYL)-N-PHENYLMETHYLBENZAMIDE | CHEMBL...) Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C14H14N2O3S/c15-20(18,19)13-8-6-12(7-9-13)14(17)16-10-11-4-2-1-3-5-11/h1-9H,10H2,(H,16,17)(H2,15,18,19)	PDB MMDB B.MOAD GoogleScholar	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	5.60	n/a	n/a	n/a	7.4	37
University of Pennsylvania					Assay Description Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...				J Am Chem Soc 123: 9620-7 (2001) Article DOI: 10.1021/ja011034p BindingDB Entry DOI: 10.7270/Q2QZ286J
					More data for this Ligand-Target Pair				3D Structure (crystal)