BDBM12061 (3S)-4-oxo-3-{[2-(3,4,5-trimethylphenoxy)benzene]sulfonamido}butanoic acid::Diphenyl Ether Sulfonamide 7

SMILES Cc1cc(Oc2ccccc2S(=O)(=O)N[C@@H](CC(O)=O)C=O)cc(C)c1C

InChI Key InChIKey=OZXOKRAILMZDOL-HNNXBMFYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12061   

TargetCaspase-1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM12061((3S)-4-oxo-3-{[2-(3,4,5-trimethylphenoxy)benzene]s...)
Affinity DataKi:  450nM ΔG°:  -9.00kcal/molepH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed