BDBM120911 US8716287, 44

SMILES COc1cc(CCN[C@@H](C)c2ccc(F)cc2)ccc1NC(=O)Nc1cnc(cn1)C#N

InChI Key InChIKey=QHAYBUJGFXDSLH-HNNXBMFYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 120911   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Sentinel Oncology

US Patent
LigandPNGBDBM120911(US8716287, 44)
Affinity DataIC50:  5.10nMpH: 7.5Assay Description:The compounds of the invention were tested for activity against Chk-1 kinase using the materials and protocols set out below. Reaction Buffer: Base R...More data for this Ligand-Target Pair
In DepthDetails US Patent