BDBM120957 US8716285, 14
SMILES ONC(=O)c1ccc2CCC(Cc2c1)Nc1nccc(n1)-c1cccc(Cl)c1
InChI Key InChIKey=BLQDCUAHMUDLRG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 120957
TargetHistone deacetylase 6(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Roche Pharmaceutical Research And Early Development
Curated by ChEMBL
Affinity DataEC50: 4.95E+3nMAssay Description:Inhibition of HDAC6 in human A549 cells assessed as tubulin acetylation after 17 to 18 hrs by cytoblot assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.66E+3nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair