BDBM12128 3-(Indol-2-yl)indazole 18::3-[5-(piperidin-1-ylmethyl)-1H-indol-2-yl]-6-(1H-pyrazol-1-yl)-1H-indazole

SMILES C(N1CCCCC1)c1ccc2[nH]c(cc2c1)-c1n[nH]c2cc(ccc12)-n1cccn1

InChI Key InChIKey=DEUPBQNMDIBCLK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12128   

TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM12128(3-(Indol-2-yl)indazole 18 | 3-[5-(piperidin-1-ylme...)
Affinity DataIC50:  2.30E+3nMAssay Description:The IMAP technology is based on the high affinity binding of phosphate by immobilized metal coordination complexes on nanoparticles. This IMAP bindin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM12128(3-(Indol-2-yl)indazole 18 | 3-[5-(piperidin-1-ylme...)
Affinity DataIC50:  110nMpH: 7.5 T: 2°CAssay Description:Kinase activity was measured in a homogeneous assay in a 96-well format. Detection was performed by HTRF using an EuK-labelled anti-phospho(S21)-GSK3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed