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BDBM121402 US8722709, 5

SMILES: NC(=O)Nc1cc(ccn1)-c1ccnn1-c1ccccc1

InChI Key: InChIKey=JXBFPZIBFVLMJE-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 121402   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mineralocorticoid receptor (MR)


(Homo sapiens (Human))
BDBM121402
PNG
(US8722709, 5)
Show SMILES NC(=O)Nc1cc(ccn1)-c1ccnn1-c1ccccc1
Show InChI InChI=1S/C15H13N5O/c16-15(21)19-14-10-11(6-8-17-14)13-7-9-18-20(13)12-4-2-1-3-5-12/h1-10H,(H3,16,17,19,21)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

n/an/a 670n/an/an/an/a7.4n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The MR competitive binding assay is based on the binding and displacement of a TAMRA-labeled Dexamethasone probe with fluorescence polarization (FP) ...


US Patent US8722709 (2014)


BindingDB Entry DOI: 10.7270/Q2NS0SJ4
More data for this
Ligand-Target Pair