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BDBM121414 US8722709, 17

SMILES: COc1cccc(c1)-n1nccc1-c1ccnc(NC(N)=O)c1

InChI Key: InChIKey=KABZRLXRMRGAPM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 121414   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mineralocorticoid receptor


(Homo sapiens (Human))
BDBM121414
PNG
(US8722709, 17)
Show SMILES COc1cccc(c1)-n1nccc1-c1ccnc(NC(N)=O)c1
Show InChI InChI=1S/C16H15N5O2/c1-23-13-4-2-3-12(10-13)21-14(6-8-19-21)11-5-7-18-15(9-11)20-16(17)22/h2-10H,1H3,(H3,17,18,20,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a>1.00E+4n/an/an/an/a7.4n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The MR competitive binding assay is based on the binding and displacement of a TAMRA-labeled Dexamethasone probe with fluorescence polarization (FP) ...


US Patent US8722709 (2014)


BindingDB Entry DOI: 10.7270/Q2NS0SJ4
More data for this
Ligand-Target Pair