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BDBM121429 US8722709, 33

SMILES: Cc1ccccc1C(Cc1ccnc(NC(N)=O)c1)C1CC1

InChI Key: InChIKey=QXYPEYSPHGCNBY-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 121429   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mineralocorticoid receptor


(Homo sapiens (Human))
BDBM121429
PNG
(US8722709, 33)
Show SMILES Cc1ccccc1C(Cc1ccnc(NC(N)=O)c1)C1CC1
Show InChI InChI=1S/C18H21N3O/c1-12-4-2-3-5-15(12)16(14-6-7-14)10-13-8-9-20-17(11-13)21-18(19)22/h2-5,8-9,11,14,16H,6-7,10H2,1H3,(H3,19,20,21,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 22n/an/an/an/a7.4n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The MR competitive binding assay is based on the binding and displacement of a TAMRA-labeled Dexamethasone probe with fluorescence polarization (FP) ...


US Patent US8722709 (2014)


BindingDB Entry DOI: 10.7270/Q2NS0SJ4
More data for this
Ligand-Target Pair