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BDBM121431 US8722709, 35

SMILES: CC(Cc1ccnc(NC(N)=O)c1)c1ccccc1

InChI Key: InChIKey=UVRSOOXLDMWIOH-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 121431   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mineralocorticoid receptor (MR)


(Homo sapiens (Human))
BDBM121431
PNG
(US8722709, 35)
Show SMILES CC(Cc1ccnc(NC(N)=O)c1)c1ccccc1
Show InChI InChI=1S/C15H17N3O/c1-11(13-5-3-2-4-6-13)9-12-7-8-17-14(10-12)18-15(16)19/h2-8,10-11H,9H2,1H3,(H3,16,17,18,19)
PDB
MMDB

KEGG

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PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 33n/an/an/an/a7.4n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The MR competitive binding assay is based on the binding and displacement of a TAMRA-labeled Dexamethasone probe with fluorescence polarization (FP) ...


US Patent US8722709 (2014)


BindingDB Entry DOI: 10.7270/Q2NS0SJ4
More data for this
Ligand-Target Pair