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BDBM121437 US8722709, 41

SMILES: Cc1ccccc1CC(C)(O)c1ccnc(NC(N)=O)c1

InChI Key: InChIKey=KZMJTRHBGYEJTN-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 121437   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mineralocorticoid receptor (MR)


(Homo sapiens (Human))
BDBM121437
PNG
(US8722709, 41)
Show SMILES Cc1ccccc1CC(C)(O)c1ccnc(NC(N)=O)c1
Show InChI InChI=1S/C16H19N3O2/c1-11-5-3-4-6-12(11)10-16(2,21)13-7-8-18-14(9-13)19-15(17)20/h3-9,21H,10H2,1-2H3,(H3,17,18,19,20)
PDB
MMDB

KEGG

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PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 1.70E+3n/an/an/an/a7.4n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The MR competitive binding assay is based on the binding and displacement of a TAMRA-labeled Dexamethasone probe with fluorescence polarization (FP) ...


US Patent US8722709 (2014)


BindingDB Entry DOI: 10.7270/Q2NS0SJ4
More data for this
Ligand-Target Pair